CNR ExploRA

Articolo in rivista, 2013, ENG, 10.1007/s00259-013-2417-8

Myocardial perfusion imaging after coronary revascularization: a clinical appraisal

Acampa, Wanda; Petretta, Maria Piera; Daniele, Stefania; Perrone-Filardi, Pasquale; Petretta, Mario; Cuocolo, Alberto

Consiglio Nazionale delle Ricerche (CNR); University of Naples Federico II; SDN Fdn; University of Naples Federico II

Revascularization procedures, including percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG), are performed in many patients with coronary artery disease. Despite the effectiveness of these procedures, different follow-up strategies need to be considered for the management of patients after revascularization. Stress myocardial perfusion single-photon emission computed tomography (MPS) is a suitable imaging method for the evaluation of patients who have undergone PCI or CABG, and it has been used in the follow-up of such patients. Radionuclide imaging is included in the follow-up strategies after PCI and CABG in patients with symptoms, but guidelines warn against routine testing of all asymptomatic patients after revascularization. After PCI, in the absence of symptoms, radionuclide imaging is recommended and indicated as appropriate after incomplete or suboptimal revascularization and in specific asymptomatic patient subsets. On the other hand, the value of MPS late after CABG in risk stratification has been demonstrated even in the absence of symptoms. Thus, given the adverse outcome associated with silent ischaemia, it can be speculated that all patients regardless of clinical status should undergo stress testing late after revascularization. Larger prospective studies are needed to assess whether stress MPS will have an impact on the outcome in asymptomatic patients after revascularization.

European journal of nuclear medicine and molecular imaging (Print) 40 (8), pp. 1275–1282