Articolo in rivista, 2015, ENG, 10.1016/j.marenvres.2015.06.018
Morelli E., Salvadori E., Basso B., Tognotti D., Cioni P., Gabellieri E.
CNR - Istituto di Biofisica
Nanotechnology has a great potential to improve life and environmental quality, however the fate of nanomaterials in the ecosystems, their bioavailability and potential toxicity on living organisms are still largely unknown, mainly in the marine environment. Genomics and proteomics are powerful tools for understanding molecular mechanisms triggered by nanoparticle exposure. In this work we investigated the effect of exposure to CdSe/ZnS quantum dots (QDs) in the marine diatom Phaeodactylum tricornutum, using different physiological, biochemical and molecular approaches. The results show that acclimation to QDs reduced the growth inhibition induced by nanoparticles in P. tricornutum cultures. The increase of glutathione observed at the end of the lag phase pointed to cellular stress. Transcriptional expression of selected stress responsive genes showed up-regulation in the QD-exposed algae. A comparison of the proteomes of exposed and unexposed cells highlighted a large number of differentially expressed proteins. To our knowledge, this is the first report on proteome analysis of a marine microalga exposed to nanoparticles.
Marine environmental research 111 , pp. 149–157
Ecotoxicology, Phytoplankton Growth, Phaeodactylum tricornutum, Glutathione, Quantum dots, Nanoparticles, Proteomics
Basso Pozzi Barbara, Gabellieri Edi, Cioni Patrizia, Morelli Elisabetta
ID: 334373
Year: 2015
Type: Articolo in rivista
Creation: 2015-10-01 12:25:43.000
Last update: 2021-04-12 10:15:28.000
CNR institutes
External IDs
CNR OAI-PMH: oai:it.cnr:prodotti:334373
DOI: 10.1016/j.marenvres.2015.06.018
PubMed: 26183536
Scopus: 2-s2.0-849451156
ISI Web of Science (WOS): 000364726000017