Articolo in rivista, 2020, ENG, 10.1016/j.apsusc.2019.145109

On the performance of laser-synthesized, SERS-based sensors for drug detection

Zanchi, C.; Giuliani, L.; Lucotti, A.; Pistaffa, M.; Trusso, S.; Neri, F.; Tommasini, M.; Ossi, P. M.

Politecnico di Milano; Consiglio Nazionale delle Ricerche; Università degli Studi di Messina

We have tested thin nano roughened Au films produced by pulsed laser deposition for quantitative SERS sensing of the anti-epileptic drug Perampanel within the range of concentrations of therapeutic interest (3 × 10 M-3 × 10 M). We propose a model to elucidate the dependence of the SERS intensity as a function of analyte concentration and contact time between the Au surface and the solution.

Applied surface science 507

Keywords

Adsorption kinetics, Antiepileptic drug, Au nanoparticles, Perampanel, Pulsed laser deposition, Surface Enhanced Raman Spectroscopy

CNR authors

Trusso Sebastiano

CNR institutes