Magnetic shape-memory (MSM) Heuslers haveattracted great attention in recent years for both caloric andmagnetomechanical applications. Thanks to their multifunctionalproperties, they are also promising for a vast variety of biomedicalapplications. However, this topic has been rarely investigated sofar. In this communication, we present the first report on theabsence of cytotoxicity of MSM Heuslers in Ni-Mn-Ga epitaxialthin films and the perspective toward bioapplications. Qualitativeand quantitative biological characterizations reveal that Ni-Mn-Ga films can promote the adhesion and proliferation of humanfibroblasts without eliciting any cytotoxic effect. Additionally, our findings show that the morphology, composition, microstructure,phase transformation, and magnetic characteristics of the films are well preserved after the biological treatments, making the materiala promising candidate for further investigations.

Magnetic Shape-Memory Heuslers Turn to Bio: Cytocompatibility of Ni-Mn-Ga Films and Biomedical Perspective

Milad Takhsha
Primo
;
Franco Furlani;Silvia Panseri;Francesca Casoli;Franca Albertini
2023

Abstract

Magnetic shape-memory (MSM) Heuslers haveattracted great attention in recent years for both caloric andmagnetomechanical applications. Thanks to their multifunctionalproperties, they are also promising for a vast variety of biomedicalapplications. However, this topic has been rarely investigated sofar. In this communication, we present the first report on theabsence of cytotoxicity of MSM Heuslers in Ni-Mn-Ga epitaxialthin films and the perspective toward bioapplications. Qualitativeand quantitative biological characterizations reveal that Ni-Mn-Ga films can promote the adhesion and proliferation of humanfibroblasts without eliciting any cytotoxic effect. Additionally, our findings show that the morphology, composition, microstructure,phase transformation, and magnetic characteristics of the films are well preserved after the biological treatments, making the materiala promising candidate for further investigations.
2023
Istituto dei Materiali per l'Elettronica ed il Magnetismo - IMEM
Istituto di Scienza, Tecnologia e Sostenibilità per lo Sviluppo dei Materiali Ceramici - ISSMC (ex ISTEC)
magnetic shape memory
Heusler alloy
epitaxial Ni-Mn-Ga film
cytotoxicity
cell adhesion
human fibroblast cell
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/430792
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